2021 Mercedes-Benz E450 Coupe Class: Premium Midsize Car Miles driven: 216 Fuel used: 9.2 gallons Real-world fuel economy: 23.5 mpg Driving mix: 50% city, 50% highway EPA-estimated fuel economy: 23/30/25 (mpg city, highway, combined) Fuel type: Premium gas required Base price: $67,450 (not including $1050 destination charge) Options on test vehicle: Graphite Gray Metallic ($720) 19-inch AMG twin 5-spoke wheels with black accents ($500), augmented video for … Continue reading Test Drive: 2021 Mercedes-Benz E450 Coupe